10 free AEMT practice questions: Toxicology and Overdose Management
These are real questions from the same bank the app draws from. Each one is written to the NREMT AEMT content specifications and kept inside the AEMT scope of practice. Pick an answer and you get the full rationale, including why the other three options are wrong.
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Question 1 of 10
A 36-year-old patient is being ventilated for a suspected opioid overdose, and vascular access is already established. A newly certified AEMT asks which routes for naloxone are inside the AEMT scope of practice. Which answer is correct?
Show the answer and rationale
Correct answer · Intravenous, intramuscular, intraosseous, and intranasal are all in scope
All four routes are inside AEMT scope for naloxone. The national scope of practice model gives the AEMT intravenous, intramuscular, intraosseous, and intranasal naloxone. Choosing between the routes is a clinical call, and scope does not limit the choice. This patient already has vascular access, and an established line is the fastest route. A combative patient is easier to dose through the nose, because no needle is needed. Intramuscular works when you have no line. Knowing all four routes are open to you means you never hold a dose while you worry about permission.
Why the others are wrong
Intranasal and intramuscular only, with the other routes left to paramedics: Intranasal and intramuscular are the two routes most services train first. Those two routes are not the limit for an AEMT. The national scope of practice model also gives the AEMT the intravenous and intraosseous routes for naloxone.
Intravenous only once access exists, with intranasal saved for a refusal: Giving naloxone through the line this patient already has is good clinical sense. Using the line is a preference, and scope does not require it. Nothing restricts the nasal route to a patient who might refuse.
Any route is in scope, though each dose needs online medical direction: Medical direction does control a lot of what an AEMT gives. Naloxone runs on standing protocol in nearly every system that carries it. You do not need an online call before each dose.
Question 2 of 10
An AEMT gives 4 mg of intranasal naloxone to a 23-year-old patient found unresponsive with pinpoint pupils and shallow breathing. The patient fell face first onto a concrete step, and there is dried blood and clot packing both nostrils. Five minutes later the mental status and the respiratory effort are unchanged, and ventilations are being delivered by BVM. The vital signs are BP 112/68, P 58, R 6, and SpO₂ 94% with ventilation. What should the AEMT do next?
Show the answer and rationale
Correct answer · Establish vascular access and give naloxone by the intravenous route
This patient still has the signs of an opioid overdose, and the intranasal naloxone most likely never got absorbed. The pupils are pinpoint, the respirations are 6, and nothing changed after the 4 mg dose. Both nostrils are packed with dried blood and clot from the fall. Intranasal naloxone only gets into the bloodstream through intact lining inside the nose. Blood and clot sit between the drug and that lining. When a drug does nothing, ask two questions. Did the drug reach the bloodstream? Was the diagnosis wrong? Here the drug probably never reached the bloodstream. Keep ventilating with the BVM, establish vascular access, and give the naloxone intravenously.
Why the others are wrong
Repeat the intranasal dose in the opposite nostril and reassess: A repeat intranasal dose makes sense when the first dose was absorbed and was just too small. Both nostrils here are packed with clot. A second dose in the other nostril lands on the same blocked lining as the first one.
Conclude the cause is not an opioid and continue ventilation alone: A drug that does nothing is a real reason to rethink the cause. Before you give up on an opioid, ask whether the naloxone ever reached the bloodstream. Nothing in this question says the naloxone did, and the pinpoint pupils and slow breathing still fit an opioid.
Wait a further ten minutes before repeating any naloxone dose: Naloxone is not instant, and patience prevents over-reversal. Ten more minutes does nothing for a blocked route. The drug is still sitting on clot instead of reaching the receptors.
Question 3 of 10
A 52-year-old patient reversed with naloxone is now alert, oriented, and refusing transport. The vital signs are BP 128/78, P 88, R 16, and SpO₂ 97% on room air. Which action best protects both the patient and the crew?
Show the answer and rationale
Correct answer · Contact medical direction and document the risks that were explained
This patient is alert and oriented after naloxone and is refusing transport. An alert, oriented adult usually understands the risk, so this patient has the right to refuse. You cannot take the decision away. The danger is renarcotization. The opioid can last longer than the naloxone, and the overdose comes back. Right now the respiratory rate is 16 and the SpO₂ is 97% on room air. Those numbers can drop once the naloxone wears off. Contact medical direction so a physician is part of the decision. Explain what re-sedation looks like and how fast re-sedation comes on. Document exactly what you explained and who was there, and follow your refusal protocol.
Why the others are wrong
Obtain a signature on the refusal form and clear the scene promptly: A signed refusal form is the normal paperwork when a patient declines care. A signature alone says nothing about the risk of re-sedation. This refusal needs that risk explained and written down.
Leave a naloxone kit with the family and advise them how to use it: Community naloxone saves lives, and leaving a kit with the family is a useful thing to do. A kit does not replace the crew. If this patient stops breathing again, a family member with a kit has no equipment to ventilate the patient.
Request law enforcement to hold the patient for a psychiatric evaluation: Overdose calls often involve mental health problems, and a hold can look like a way to keep this patient safe. This patient is alert and oriented. Nothing in this question supports taking away the patient's right to decide.
Question 4 of 10
A 26-year-old patient is agitated and paranoid at a music festival. The pupils are dilated, the skin is hot and soaked with sweat, and the patient keeps pulling away from the crew. The vital signs are BP 168/96, P 138, R 24, T 103.4, and SpO₂ 98% on room air. Which toxidrome do these findings describe?
Show the answer and rationale
Correct answer · Sympathomimetic
These findings describe the sympathomimetic toxidrome. The pupils are dilated, the pulse is 138, the blood pressure is 168/96, the temperature is 103.4, and the patient is agitated. Every one of those findings means the body is sped up. Two toxidromes speed the body up like this, sympathomimetic and anticholinergic. The skin tells the two apart. Sympathomimetic drugs stimulate the same receptors your body uses under stress. Sweating is part of the stress response, so the skin stays wet. Anticholinergic drugs block the receptors that make sweat, so anticholinergic skin is hot and dry. This patient's skin is hot and soaked with sweat.
Why the others are wrong
Anticholinergic: poisoning matches almost everything here. Dilated pupils, a fast heart, a hot patient, and an altered mental status all fit. Anticholinergic skin is hot and dry, and this patient is soaked with sweat.
Cholinergic: poisoning also makes the skin wet. Everything else goes the other way. A cholinergic patient has constricted pupils and a slow heart rate, and this patient has dilated pupils and a pulse of 138.
Sedative-hypnotic: Alcohol and benzodiazepines are a fair guess for an unknown ingestion at a festival. Sedative-hypnotic patients are quiet, slow, and hypotensive. This patient is agitated, with a blood pressure of 168/96.
Question 5 of 10
A 61-year-old patient collapsed while mixing pesticide concentrate in a barn. The clothing is soaked, saliva is running from the mouth, there has been loss of urine and stool, and wheezes are heard throughout both lungs. The pupils are constricted. The vital signs are BP 98/56, P 44, R 30, and SpO₂ 88% on room air. Which toxidrome do these findings describe?
Show the answer and rationale
Correct answer · Cholinergic
These findings describe the cholinergic toxidrome. Saliva is running from the mouth, the clothing is soaked, and there has been loss of urine and stool. The pupils are constricted, the pulse is 44, and wheezes are heard in both lungs. Cholinergic poisoning makes the body wet in every way at once. SLUDGE is the mnemonic: salivation, lacrimation, urination, defecation, gastrointestinal distress, and emesis. On top of SLUDGE you get a slow heart rate, secretions pouring into the airways, and bronchospasm. Organophosphate pesticides and nerve agents are the exposures that cause cholinergic poisoning.
Why the others are wrong
Opioid: An opioid overdose also gives you constricted pupils and a depressed patient. Opioid skin is normal and dry. An opioid patient is not losing saliva, urine, and stool the way this patient is.
Anticholinergic: poisoning fits a patient who is hot and dry, with dilated pupils. This patient is wet everywhere, with constricted pupils.
Sympathomimetic: The wet skin and the respiratory rate of 30 fit a sympathomimetic patient. A sympathomimetic drug also gives you dilated pupils and a racing heart. This patient's pupils are constricted and the pulse is 44.
Question 6 of 10
A 66-year-old patient with hypertension swallowed a bottle of metoprolol about two hours ago and is now weak and lightheaded. The skin is cool, the lungs are clear, and the patient answers questions slowly. The vital signs are BP 76/44, P 38, R 16, and SpO₂ 95% on room air. What should the AEMT do?
Show the answer and rationale
Correct answer · Start vascular access with fluid per protocol and request a paramedic intercept
This patient has a beta blocker overdose from the metoprolol. The pulse is 38, the blood pressure is 76/44, and the skin is cool. Metoprolol blocks the beta receptor on the heart. The heart cannot respond to the body's own adrenaline the normal way. That's why the slow rate and the low pressure do not respond well to the usual treatments. Glucagon is the antidote for this overdose. You carry glucagon for low blood sugar, but glucagon as an antidote for a beta blocker overdose is a paramedic treatment. Your job is to get everything ready for the paramedic. Start vascular access, give fluid per protocol, put the monitor on, and request a paramedic intercept.
Why the others are wrong
Apply the automated external defibrillator and follow the advisory prompts: A pulse of 38 is dangerously slow, and the automated external defibrillator is right there. An AED is for a patient in cardiac arrest who has no pulse. This patient still has a pulse and is answering questions.
Give oral glucose for the weakness and monitor the mental status: Weakness and slow answers do fit low blood sugar, and checking a glucose level is always fair. Oral glucose does nothing for a pulse of 38 and a pressure of 76/44. Those numbers come from the metoprolol this patient swallowed.
Give high-concentration oxygen and transport without vascular access: Getting this patient moving toward the hospital is right, and skipping the line saves a minute. A pressure of 76/44 needs fluid, and fluid needs vascular access. A line already in place also lets the paramedic give the antidote the moment the paramedic arrives.
Question 7 of 10
A 15-year-old patient swallowed about thirty acetaminophen tablets two hours ago after an argument and now says it was a mistake and feels fine. The skin is warm and dry, the abdomen is soft, and the vital signs are BP 116/72, P 82, R 16, and SpO₂ 99% on room air. What should the AEMT do?
Show the answer and rationale
Correct answer · Transport and document the time and the amount of the ingestion
This patient took an acetaminophen overdose of about thirty tablets two hours ago. The patient now feels fine, the skin is warm and dry, the abdomen is soft, and the vital signs are normal. Acetaminophen overdose often looks this normal early on. A patient who swallowed a whole bottle can feel fine for the first day. The liver failure shows up days later. Feeling fine does not mean the patient took only a little. Transport every acetaminophen overdose. Write down the time and the amount as carefully as you can. The hospital bases the treatment decision on that timeline.
Why the others are wrong
Advise the family to watch for symptoms at home overnight: A normal exam makes watching at home sound reasonable. The liver injury from acetaminophen shows up days later. By then, the window to prevent the liver injury has closed.
Have the patient drink water to dilute the tablets before transport: Drinking water to dilute a poison is common home first aid. Water does not reduce how much acetaminophen gets absorbed. Drinking water also raises the risk of vomiting in a patient you are about to move.
Give activated charcoal on scene and reassess the mental status: Activated charcoal does bind acetaminophen, and this ingestion is recent. Most ambulances no longer carry charcoal, and giving charcoal is a protocol decision, not a routine step. Even when charcoal is available, it never replaces transport.
Question 8 of 10
Three coworkers are found together in a break room, each reporting headache, nausea, and confusion after running a portable generator indoors overnight during a power outage. Pulse oximetry reads 98% on each patient, and skin color appears normal. Which finding most likely explains the oxygen saturation reading?
Show the answer and rationale
Correct answer · Carboxyhemoglobin is read by the pulse oximeter as normally saturated hemoglobin
These patients have carbon monoxide poisoning. Three coworkers from the same closed room all have headache, nausea, and confusion after running a generator indoors overnight. Carbon monoxide binds to hemoglobin, and hemoglobin carrying carbon monoxide is called carboxyhemoglobin. A standard pulse oximeter cannot tell carboxyhemoglobin apart from hemoglobin carrying oxygen. The pulse oximeter reads 98%, even though the blood is carrying far less oxygen the body can use. Get the patients out of the room, give high-concentration oxygen, and transport. Hyperbaric treatment is a decision for the hospital.
Why the others are wrong
The generator exhaust displaced enough oxygen in the room to cause hypoxia: Running a generator indoors overnight does not use up enough of the room's oxygen to cause this. The danger is the carbon monoxide the patients breathe in, which binds to hemoglobin. Low room oxygen also would not explain why the pulse oximeter reads normal in patients who are not getting enough oxygen.
Hyperventilation from anxiety is producing a falsely elevated reading: Hyperventilation does not make a pulse oximeter read falsely high. Breathing rate does not change how a standard pulse oximeter works. Anxiety also would not explain why three coworkers have the same findings.
The patients are in the early, compensated stage of shock: Compensated shock is a blood flow problem where the blood pressure is still holding up. Compensated shock does not explain a falsely normal oxygen saturation. Shock also does not fit three patients with headache, nausea, and confusion after the same exposure.
Question 9 of 10
A 24-year-old patient tells the AEMT they swallowed a handful of acetaminophen tablets about 20 minutes ago in a suicide attempt. The patient is alert, oriented, and speaking clearly, with no difficulty breathing; BP 122/76, P 88, R 16, SpO₂ 99%. Local protocol permits activated charcoal for appropriate ingestions with an order from medical control. What should the AEMT do next?
Show the answer and rationale
Correct answer · Contact medical control for an order to give activated charcoal
Contact medical control for an order to give activated charcoal. Activated charcoal binds the swallowed drug in the stomach and intestines so the body does not absorb the drug. Charcoal works best within about an hour of the ingestion. This patient swallowed the acetaminophen 20 minutes ago, which is well inside that window. Charcoal is not given to a patient who cannot protect the airway because of a decreased level of consciousness. This patient is alert, oriented, and speaking clearly, so that contraindication is not there. Before you give charcoal, you need approval from medical control. The local protocol allows charcoal with an order, so calling medical control is your next step.
Why the others are wrong
Withhold charcoal because acetaminophen is not adsorbed by activated charcoal: Withholding charcoal is right for a substance charcoal cannot bind. Acetaminophen is not one of those substances. Timing is what matters here, and this ingestion was 20 minutes ago, well inside the window of about an hour.
Give activated charcoal immediately without contacting medical control first: Activated charcoal is the right drug for this patient, given in the wrong order. You need the order from medical control before you give charcoal, not after.
Withhold charcoal because the patient's level of consciousness is decreased: A decreased level of consciousness is a reason to withhold charcoal. This patient is alert, oriented, and speaking clearly, so that reason does not apply.
Question 10 of 10
A 45-year-old patient reports headache, nausea, and dizziness that began at home during a furnace malfunction. Before oxygen is applied, SpO₂ reads 99% on room air. High-flow oxygen is applied by nonrebreathing mask, and reassessment 10 minutes later shows the headache has improved from severe to mild, the dizziness has resolved, and SpO₂ still reads 99%. What should the AEMT do based on this reassessment?
Show the answer and rationale
Correct answer · Improvement confirms CO poisoning; continue oxygen and transport
This patient has carbon monoxide poisoning, and the oxygen is working. The headache, nausea, and dizziness started during a furnace malfunction. Ten minutes of high-flow oxygen took the headache from severe to mild, and the dizziness went away. The pulse oximeter measures how saturated the hemoglobin is. The pulse oximeter cannot tell oxygen from carbon monoxide on the hemoglobin. That's why the SpO₂ reads a normal 99% in carbon monoxide poisoning, before and after treatment. The improving symptoms show you the patient is responding, not the SpO₂. Keep the high-flow oxygen on and transport. Do not turn the oxygen down or stop the oxygen based on the SpO₂.
Why the others are wrong
Improvement confirms CO poisoning; reduce oxygen to titrate SpO₂: The improving symptoms do confirm carbon monoxide poisoning. Turning the oxygen down to match the SpO₂ is the mistake. The SpO₂ is not reliable in carbon monoxide poisoning, because the sensor cannot tell oxygen from carbon monoxide.
Normal SpO₂ rules out CO poisoning; consider psychogenic causes: A normal SpO₂ would reassure you in most patients. In carbon monoxide poisoning, the sensor reads carbon monoxide as oxygen, so a normal SpO₂ does not rule the poisoning out. The headache, the dizziness, and the furnace malfunction all point to carbon monoxide.
Normal SpO₂ confirms adequate oxygenation; discontinue oxygen: An SpO₂ of 99% usually means the patient has enough oxygen. Here the 99% is a false reading caused by carbon monoxide on the hemoglobin. Stopping the oxygen takes away the treatment that is making this patient better.
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Airway, Respiration & Ventilation
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- Neurologic Emergencies: Stroke, Seizure, and Altered Mental Status
- Endocrine Emergencies Beyond Diabetes
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- Toxicology and Overdose Management
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